All specialtiesOphthalmology
Ophthalmology Evidence Evolution
5 evidence evolution narratives tracing how landmark trials and guideline updates reshaped ophthalmology practice.
27.12000-2024
Anti-VEGF Therapy for Wet AMD
Saving sight with injections
Laser → PDT → ranibizumab (MARINA/ANCHOR 2006) → bevacizumab (CATT) → aflibercept → treat-and-extend → biosimilars
MARINAANCHORCATTVIEWYing IVAN
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27.22005-2024
SLT as First-Line Glaucoma Treatment
Laser before drops
Drops first → LiGHT (2019) SLT first → cost-effective → drop-free initial management
LiGHTGLTSLT/Med Study
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27.32010-2024
AI in Diabetic Retinopathy Screening
Autonomous diagnosis
Ophthalmologist-only → teleretinal → IDx-DR first FDA AI (2018) → autonomous screening → integration
IDx-DR pivotalEyeArt
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27.41990-2024
Cataract IOL Technology
Tailoring the artificial lens
Monofocal → multifocal → EDOF → toric → LAL → femtosecond → patient selection
FDA approval studiesRxSight LAL
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27.52000-2024
OCT in Retinal Disease
Imaging the invisible
Clinical exam + FA → time-domain OCT → SD-OCT → swept-source → OCTA → AI interpretation
OCT retinal trialsAREDS
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