Landmark TrialRCTRandomized Controlled Trial
Prevention of Recurrent Preterm Delivery by 17 Alpha-Hydroxyprogesterone Caproate
New England Journal of Medicine2003IF: 25.4
Paul J. Meis Mark A. Klebanoff Elizabeth Thom Mitchell P. Dombrowski Baha M. Sibai Atef H. Moawad Catherine Y. Spong John C. Hauth Menachem Miodovnik Michael W. Varner Kenneth J. Leveno Steve N. Caritis Jay D. Iams Ronald J. Wapner Deborah Conway Mary J. O’Sullivan Marshall W. Carpenter Brian M. Mercer Susan M. Ramin John M. Thorp Alan M. Peaceman Steven G. Gabbe
Abstract
Weekly injections of 17P resulted in a substantial reduction in the rate of recurrent preterm delivery among women who were at particularly high risk for preterm delivery and reduced the likelihood of several complications in their infants.