Landmark TrialCohort Study
Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy
Annals of Surgery2004IF: 4.0
René Adam, V. Delvart, Gérard Pascal, Adrian Valeanu, Denis Castaing, Daniel Azoulay, Sylvie Giacchetti, Bernard Paule, F Kunstlinger, O Ghémard, Françis Lévi, Henri Bismuth
Abstract
Modern chemotherapy allows 12.5% of patients with unresectable CRLM to be rescued by liver surgery. Despite a high rate of recurrence, 5-year survival is 33% overall, with a wide use of repeat hepatectomies and extrahepatic resections. Four preoperative risk factors could select the patients most likely to benefit from this strategy.