RCTRandomized Controlled Trial
Intensive Insulin Therapy in the Medical ICU
New England Journal of Medicine2006IF: 25.4
Greet Van den Berghe, Alexander Wilmer, Greet Hermans, Wouter Meersseman, Pieter Wouters, Ilse Milants, Eric Van Wijngaerden, Herman Bobbaers, Roger Bouillon
Abstract
Intensive insulin therapy significantly reduced morbidity but not mortality among all patients in the medical ICU. Although the risk of subsequent death and disease was reduced in patients treated for three or more days, these patients could not be identified before therapy. Further studies are needed to confirm these preliminary data. (ClinicalTrials.gov number, NCT00115479.)