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Evidence Evolution
Evidence Evolution
Landmark TrialRCTRandomized Controlled Trial

Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration

New England Journal of Medicine2011IF: 25.4

The CATT Research Group

PMID: 21526923View on PubMedDOI

Abstract

At 1 year, bevacizumab and ranibizumab had equivalent effects on visual acuity when administered according to the same schedule. Ranibizumab given as needed with monthly evaluation had effects on vision that were equivalent to those of ranibizumab administered monthly. Differences in rates of serious adverse events require further study. (Funded by the National Eye Institute; ClinicalTrials.gov number, NCT00593450.).

Specialty

Ophthalmology

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