Landmark TrialRCTRandomized Controlled Trial
Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary Embolism
New England Journal of Medicine2012IF: 25.4
The EINSTEIN–PE Investigators
Abstract
A fixed-dose regimen of rivaroxaban alone was noninferior to standard therapy for the initial and long-term treatment of pulmonary embolism and had a potentially improved benefit-risk profile. (Funded by Bayer HealthCare and Janssen Pharmaceuticals; EINSTEIN-PE ClinicalTrials.gov number, NCT00439777.).