Landmark TrialMeta Analysis
Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology2012
Philip C De Witt Hamer, Santiago Gil Robles, Aeilko H Zwinderman, Hugues Duffau, Mitchel S Berger
Abstract
Surgery for infiltrative gliomas aims to balance tumor removal with preservation of functional integrity. The usefulness of intraoperative stimulation mapping (ISM) has not been addressed in randomized trials. This study addresses glioma surgery outcome on the basis of a meta-analysis of observational studies.