Landmark TrialRCTRandomized Controlled Trial
A Comparison of Outcomes in Men 11 Years after Heart-Valve Replacement with a Mechanical Valve or Bioprosthesis
New England Journal of Medicine1993IF: 25.4
Karl E. Hammermeister, Gulshan K. Sethi, William G. Henderson, Charles Oprian, Tai Kim, Shahbudin H. Rahimtoola
Abstract
After 11 years, the rates of survival and freedom from all valve-related complications were similar for patients who received mechanical heart valves and those who received bioprosthetic heart valves. However, structural failure was observed only with the bioprosthetic valves, whereas bleeding complications were more frequent among patients who received mechanical valves.