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Landmark TrialRCTRandomized Controlled Trial

A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus

New England Journal of Medicine1998IF: 25.4

David M. Treiman, Patti D. Meyers, Nancy Y. Walton, Joseph F. Collins, Cindy Colling, A. James Rowan, Adrian Handforth, Edward Faught, Vincent P. Calabrese, Basim M. Uthman, R. Eugene Ramsay, Meenal B. Mamdani, Pratap M. Yagnik, J.C. Jones, Elizabeth Barry, Jane Boggs, Andrés M. Kanner

PMID: 9738086View on PubMedDOI

Abstract

As initial intravenous treatment for overt generalized convulsive status epilepticus, lorazepam is more effective than phenytoin. Although lorazepam is no more efficacious than phenobarbital or diazepam plus phenytoin, it is easier to use.

Specialty

Neurology

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