Landmark TrialRCTRandomized Controlled Trial
A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care
New England Journal of Medicine1999IF: 25.4
Paul C. Hébert, George A. Wells, Morris A. Blajchman, John C. Marshall, Claudio M. Martin, Giuseppe Pagliarello, Martin Tweeddale, Irwin Schweitzer, Elizabeth Yetisir
Abstract
A restrictive strategy of red-cell transfusion is at least as effective as and possibly superior to a liberal transfusion strategy in critically ill patients, with the possible exception of patients with acute myocardial infarction and unstable angina.