All Pathways
PsychiatryEmergency

Catatonia Assessment & Treatment (BAP Guidelines)

Catatonia Assessment & Treatment (BAP Guidelines): Suspected Catatonia → Bush-Francis Catatonia Rating Scale (BFCRS) → BFCRS Screen Result → Screen Nega...

Interactive Decision Tree

Mini Map

Algorithm Steps

  1. Start

    Suspected Catatonia

    Patient with motor/behavioral abnormalities suggesting catatonia

    1. Action

      Bush-Francis Catatonia Rating Scale (BFCRS)

      14-item screening (first 14 items)

      • 1. Excitement - extreme hyperactivity
      • 2. Immobility/stupor - extreme hypoactivity
      • 3. Mutism - no/minimal verbal response
      • 4. Staring - fixed gaze, poor eye contact
      • 5. Posturing - maintaining positions spontaneously
      • 6. Grimacing - maintenance of odd expressions
      • 7. Echopraxia/echolalia - mimicking
      • 8. Stereotypy - repetitive movements
      • 9. Mannerisms - odd purposeful movements
      • 10. Verbigeration - repetition of phrases
      • 11. Rigidity - resistance to movement
      • 12. Negativism - opposing/no response to stimuli
      • 13. Waxy flexibility - maintains examiner-imposed position
      • 14. Withdrawal - refusal to eat/drink/make eye contact
      1. Decision

        BFCRS Screen Result

        Score ≥2 on screening items is positive

        1. Action

          Screen Negative

          BFCRS <2, consider other diagnoses

          • Depression with psychomotor retardation
          • Schizophrenia negative symptoms
          • Parkinsonism
          • Non-convulsive status epilepticus
          • Akinetic mutism (frontal lesion)
        2. Action

          Screen Positive (≥2)

          Complete full 23-item BFCRS

          1. Action

            Medical Workup

            Rule out organic causes

            • CBC, BMP, LFTs, TFTs
            • CK (elevated in catatonia)
            • Lumbar puncture (anti-NMDAR encephalitis)
            • Brain MRI
            • EEG (rule out NCSE)
            • Toxicology screen
            • Consider autoimmune panel
            1. Decision

              Signs of Malignant Catatonia?

              Medical emergency

              • Fever/hyperthermia
              • Autonomic instability
              • Altered consciousness
              • Very high CK levels
              1. Warning

                ⚠️ MALIGNANT CATATONIA

                Life-threatening emergency

                • ICU admission
                • IV fluids, cooling if hyperthermic
                • High-dose benzodiazepines
                • URGENT ECT consultation
                • Mortality high if untreated
                1. Action

                  Electroconvulsive Therapy (ECT)

                  Highly effective for catatonia

                  • Response rate 80-100% (even if benzo-resistant)
                  • Bilateral electrode placement preferred
                  • Daily or every-other-day initially
                  • Continue until symptoms resolve
                  • May need maintenance ECT
                  • Continue benzodiazepines during ECT
                  1. Outcome

                    Resolution & Maintenance

                    Taper treatment gradually

                    • Continue treatment 2-4 weeks after resolution
                    • Slow benzodiazepine taper
                    • Treat underlying condition
                    • Monitor for recurrence
                    • May need maintenance ECT for recurrent catatonia
              2. Action

                Lorazepam Challenge Test

                Diagnostic and therapeutic

                • Lorazepam 1-2mg IV or IM
                • Observe for 15-30 minutes
                • Positive response: ≥50% reduction in BFCRS
                • Response supports catatonia diagnosis
                • May need to repeat for full response
                1. Decision

                  Response to Lorazepam?

                  Assess within 30 minutes

                  1. Action

                    Benzodiazepine Maintenance

                    Continue scheduled lorazepam

                    • Lorazepam 2mg IV/IM q4-8h scheduled
                    • Titrate up to response (may need 8-24mg/day)
                    • Maximum response typically in 3-7 days
                    • Monitor for respiratory depression
                    • Taper gradually once symptoms resolve
                    1. Warning

                      ⚠️ Medications to AVOID

                      Can worsen catatonia

                      • AVOID antipsychotics initially (may worsen catatonia)
                      • If must use: low-dose atypical after benzos started
                      • AVOID if any NMS features present
                      • First-gen antipsychotics: higher NMS risk
                  2. Action

                    No/Partial Response

                    Consider ECT or augmentation

                    • If no response after 3-7 days of adequate lorazepam
                    • Consider adding: Amantadine 100mg BID or Memantine
                    • Proceed to ECT evaluation

Guideline Source

Evidence-Based Consensus Guidelines for the Management of Catatonia: Recommendations from the British Association for Psychopharmacology

Clinical Safety Information

Clinical Decision Support — Not a Substitute for Clinical Judgment

Individual patient factors may require deviation from these recommendations.

Known Limitations

  • Catatonia can be caused by medical, neurological, or psychiatric conditions
  • Always rule out organic causes before treating as psychiatric catatonia
  • Malignant catatonia is life-threatening and requires urgent ECT
  • Anti-NMDA receptor encephalitis mimics catatonia

Applicable Regions

USEUGlobal
Version 1Next review: 2027-01-11

Frequently Asked Questions

What is the Catatonia Assessment & Treatment (BAP Guidelines)?

The Catatonia Assessment & Treatment (BAP Guidelines) is a emergency clinical algorithm for Psychiatry. It provides a structured decision tree to guide clinical decision-making, based on Evidence-Based Consensus Guidelines for the Management of Catatonia: Recommendations from the British Association for Psychopharmacology.

What guideline is the Catatonia Assessment & Treatment (BAP Guidelines) based on?

This algorithm is based on Evidence-Based Consensus Guidelines for the Management of Catatonia: Recommendations from the British Association for Psychopharmacology (DOI: 10.1177/02698811231158232).

What are the limitations of the Catatonia Assessment & Treatment (BAP Guidelines)?

Known limitations include: Catatonia can be caused by medical, neurological, or psychiatric conditions; Always rule out organic causes before treating as psychiatric catatonia; Malignant catatonia is life-threatening and requires urgent ECT; Anti-NMDA receptor encephalitis mimics catatonia. Individual patient factors may require deviation from these recommendations.

Get AI-Powered Analysis Alongside This Algorithm

In AttendMe.ai, the Catatonia Assessment & Treatment (BAP Guidelines) appears automatically when your clinical question matches — alongside evidence from 3M+ peer-reviewed articles.

Try AttendMe Free