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Acute Compartment Syndrome Management (AAOS 2025)

Acute Compartment Syndrome Management (AAOS 2025): Suspected acute compartment syndrome (adult limb) → At-risk patient: check hourly and keep a low thre...

Pathway Overview

19 steps

Algorithm Steps

19 total

  1. 01Start

    Suspected acute compartment syndrome (adult limb)

    Surgical emergency. Call the orthopaedic registrar or consultant early.

  2. 02Action

    At-risk patient: check hourly and keep a low threshold

    Know the causes. Any of these plus pain or swelling needs ACS assessment.

    • Tibial shaft fracture (most common) or forearm fracture
    • Crush injury or high-energy trauma
    • Reperfusion after vascular repair or revascularisation
    • Tight cast, splint or circumferential dressing
    • Prolonged limb compression or immobilisation (e.g. overdose, long surgery, lithotomy position)
    • Circumferential burn
    • IV or IO fluid extravasation
    • Anticoagulant or bleeding disorder
  3. 03Warning

    Unreliable exam (obtunded, sedated, nerve block) or child: monitor pressure

    Pain may be absent. Children: rising analgesic need, anxiety and agitation are early signs; get paediatric orthopaedic advice.

    • Obtunded or sedated: repeat or continuous compartment pressure until ACS is diagnosed or excluded
    • Neuraxial or regional block may hide pain: examine often and/or monitor pressure
    • Maintain perfusion; avoid hypotension
  4. 04Action

    Assess now and hourly: pain out of proportion, pain on passive stretch

    ACS is a clinical diagnosis. A palpable pulse does NOT exclude it. Record each exam with the time.

    • Pain out of proportion to the injury
    • Pain on passive stretch of the compartment muscles
    • Rising analgesic need (record dose and time)
    • Tense, swollen compartment
    • Paraesthesia or numbness (later sign)
    • Weakness or paralysis (late sign; poor prognosis)
    • Pallor and absent pulse are very late; pulses are usually present
  5. 05Action

    All patients: split the cast and release dressings now

    Do this at once. It must not delay theatre when ACS is clear.

    • Split the cast and padding down to skin; release all circumferential dressings
    • Keep the limb at heart level; do not raise it (elevation lowers perfusion pressure)
    • Correct hypotension
    • Senior review; reassess within 30 minutes
  6. 06Decision

    Clear clinical ACS on a reliable exam?

    Yes: go to the late-ACS check, then theatre. No, equivocal or exam unreliable: measure pressure.

  7. If Yes
    1. 07Decision

      Late or missed ACS with established irreversible damage?

      Senior decision (two consultants). Time since onset or numbness alone does NOT prove it. If in doubt, decompress.

    2. If Yes
      1. 08Warning

        Late ACS with established necrosis: do NOT perform fasciotomy

        Example: found down, long unknown duration, with myoglobinuria, renal failure and very high CK. Fracture: external fixation or cast that does not open the compartment.

        • Two consultants decide and document; a small incision to check muscle viability may be reasonable; if muscle is dead, do not extend it
        • Fasciotomy on dead muscle risks reperfusion injury, infection, sepsis and amputation
        • Treat rhabdomyolysis: check potassium, CK and creatinine; IV fluids (heart failure or oliguric AKI: ICU or renal advice)
      2. 09Outcome

        Late ACS: non-operative care; amputation if limb not viable or sepsis

        Senior team plan. Watch for hyperkalaemia, AKI and infection.

      If No
      1. 10Action

        Viable or uncertain tissue: emergency fasciotomy now

        Decompress fully and immediately once ACS is diagnosed. Not for late ACS with established necrosis (senior decision).

        • Open every involved compartment completely (leg: all 4, by the recommended two-incision technique)
        • Crush or long ischaemia: check potassium before and after release; tell the anaesthetist (reperfusion hyperkalaemia)
        • On an anticoagulant: plan reversal with the anaesthetist; do not delay decompression
        • Debride dead muscle; record the viability of each compartment; leave the wounds open
        • Forearm: volar incision; add a dorsal incision if the dorsal compartment stays tight
      2. 11Action

        If a long-bone fracture: stabilise it at the same operation

        Operative fixation (external or internal) for initial stabilisation.

        • Choose external or internal fixation by the soft tissues, contamination and the patient's condition
      3. 12Action

        After decompression: watch for reperfusion injury and rhabdomyolysis

        Highest risk after crush, long ischaemia or late presentation.

        • Check potassium, CK and creatinine; test urine for myoglobin (blood on dipstick)
        • Monitor urine output hourly
        • IV crystalloid to keep a good urine output (see rhabdomyolysis pathway); heart failure or oliguric AKI: fluid plan with ICU or renal team
        • Treat hyperkalaemia at once (see hyperkalaemia pathway)
      4. 13Action

        Wound care: plastics review within 24 h; re-look within 72 h

        Plan definitive closure or cover.

        • Discuss with a plastic surgeon within 24 h of fasciotomy
        • Re-look and debride within 72 h, or earlier if needed
        • Negative pressure wound therapy may shorten time to closure and reduce skin grafting
        • Close by delayed primary closure, gradual closure (e.g. vessel loops) or skin graft
      5. 14Outcome

        Compartments decompressed

        Continue rhabdomyolysis checks and planned wound closure.

    If No
    1. 15Action

      Equivocal or unreliable exam: measure compartment pressures

      Delta P = diastolic BP minus compartment pressure. Measure BP at the same time.

      • Measure all suspected compartments with a validated device, near the fracture level
      • Under general anaesthesia diastolic BP falls (mean 18 mmHg): delta P can be falsely low; compare with the pre-operative diastolic BP
      • Repeated or continuous measurement is better than one reading
      • No single absolute pressure defines ACS
    2. 16Decision

      Delta P 30 mmHg or less?

      Yes: consultant decision on fasciotomy now. No: ACS unlikely now; keep monitoring.

    3. If Yes
      1. 17Action

        Delta P 30 mmHg or less: consultant decides on fasciotomy now

        Combine the pressure with the clinical picture. Do not wait for late signs. If the consultant chooses to keep monitoring: hourly exam and repeat or continuous pressures; decide again at each check.

        • A single low reading can overcall ACS; repeat if the picture is unclear and time allows
        • Continuous monitoring: delta P below 30 mmHg for more than 2 hours was the fasciotomy threshold in the largest series
        • Absolute pressure above 40 mmHg: consider urgent decompression
        • At-risk patient with equivocal findings: fasciotomy is less harmful than a missed ACS
      2. Path rejoins step 07Shared downstream outcome
      If No
      1. 18Action

        Delta P more than 30 mmHg: ACS unlikely now; keep monitoring

        One reading does not rule out ACS. ACS can still develop. Continue while the risk persists.

        • Hourly clinical exam with documented findings
        • Repeat or continuous pressure measurement
        • Delta P falls to 30 mmHg or less, absolute pressure above 40 mmHg, or signs progress: consultant review for urgent fasciotomy
        • Senior review of the plan
      2. 19Outcome

        ACS not present on serial assessment

        Keep hourly checks while the risk persists. Any new sign: repeat pressure and senior review.

Guideline Source

AAOS Management of Acute Compartment Syndrome Evidence-Based Clinical Practice Guideline (2025 rapid update of the 2018 guideline)

Clinical Safety Information

Clinical Decision Support — Not a Substitute for Clinical Judgment

Individual patient factors may require deviation from these recommendations.

Known Limitations

  • Adults only. Children: signs differ (rising analgesic need, anxiety, agitation); get paediatric orthopaedic advice.
  • Evidence is limited; most AAOS statements are consensus. Pressure thresholds support, and do not replace, senior clinical judgement.
  • Does not cover chronic exertional compartment syndrome.
  • Foot and hand compartment syndrome: no consensus on management; follow local senior advice.

Contraindicated Populations

pediatric

Applicable Regions

USEUUKAUGlobal

AU: No national Australian guideline; AAOS and BOASt standards are used. Escalate to the on-call orthopaedic consultant; retrieval for remote sites without theatre access.

UK: BOASt Compartment Syndrome of the Extremities (updated July 2025): hourly assessment, immediate decompression, plastics discussion within 24 h, re-look within 72 h.

Version 2Next review: 2027-09-30

Frequently Asked Questions

What is the Acute Compartment Syndrome Management (AAOS 2025)?

The Acute Compartment Syndrome Management (AAOS 2025) is a emergency clinical algorithm for Orthopedic Surgery. It provides a structured decision tree to guide clinical decision-making, based on AAOS Management of Acute Compartment Syndrome Evidence-Based Clinical Practice Guideline (2025 rapid update of the 2018 guideline).

What guideline is the Acute Compartment Syndrome Management (AAOS 2025) based on?

This algorithm is based on AAOS Management of Acute Compartment Syndrome Evidence-Based Clinical Practice Guideline (2025 rapid update of the 2018 guideline).

What are the limitations of the Acute Compartment Syndrome Management (AAOS 2025)?

Known limitations include: Adults only. Children: signs differ (rising analgesic need, anxiety, agitation); get paediatric orthopaedic advice.; Evidence is limited; most AAOS statements are consensus. Pressure thresholds support, and do not replace, senior clinical judgement.; Does not cover chronic exertional compartment syndrome.; Foot and hand compartment syndrome: no consensus on management; follow local senior advice.. Individual patient factors may require deviation from these recommendations.

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