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Pediatric Cardiac Arrest (PALS 2025)

Pediatric Cardiac Arrest (PALS 2025): Pediatric Cardiac Arrest → Start High-Quality CPR → Attach Monitor/Defibrillator + IV/IO Access → Rhythm Check: Sh...

Pathway Overview

12 steps

Algorithm Steps

12 total

  1. 01Start

    Pediatric Cardiac Arrest

    Unresponsive child, no pulse, not breathing normally

  2. 02Action

    Start High-Quality CPR

    Begin CPR immediately while preparing for rhythm analysis

    • Push hard (≥1/3 AP diameter): Infants 4cm, Children 5cm
    • Push fast: 100-120 compressions/min
    • Allow complete chest recoil
    • Minimize interruptions (<10 sec)
    • Compression:ventilation ratio: 15:2 (2 rescuers), 30:2 (1 rescuer)
    • If advanced airway: continuous compressions, 1 breath q2-3 sec
  3. 03Action

    Attach Monitor/Defibrillator + IV/IO Access

    Attach pads in anterior-posterior or anterior-lateral position

    • Use pediatric pads/dose attenuator for <25 kg if available
    • Adult pads acceptable if pediatric not available
    • Establish IV or IO access (IO preferred if IV not rapid)
  4. 04Decision

    Rhythm Check: Shockable?

    Is the rhythm VF or pulseless VT?

  5. 05Action

    Defibrillation

    Shock for VF/pVT

    • First shock: 2 J/kg
    • Subsequent shocks: 4 J/kg (max 10 J/kg or adult dose)
    • Resume CPR immediately for 2 minutes after shock
    • Minimize peri-shock pause
  6. 06Action

    Epinephrine (after 2nd shock)

    Give epinephrine if VF/pVT persists after initial shock

    • Epinephrine: 0.01 mg/kg IV/IO (max 1 mg)
    • Repeat every 3-5 minutes
    • Can give via ETT: 0.1 mg/kg if no IV/IO
  7. 07Action

    Antiarrhythmic for Refractory VF/pVT

    Consider after 2-3 shocks

    • Amiodarone: 5 mg/kg IV/IO bolus (max 300 mg)
    • May repeat x2 for refractory VF/pVT
    • OR Lidocaine: 1 mg/kg IV/IO (if amiodarone unavailable)
  8. 08Decision

    ROSC?

    Check for return of spontaneous circulation every 2 minutes

  9. 09Outcome

    Post-Cardiac Arrest Care

    ROSC achieved - initiate post-arrest care

    • Optimize ventilation and oxygenation (SpO2 94-99%)
    • Avoid hyperventilation
    • Maintain BP with fluids/vasopressors
    • Obtain 12-lead ECG
    • Consider targeted temperature management
    • Identify and treat underlying cause
    • Transfer to PICU
  10. 10Action

    Continue Resuscitation

    Continue CPR cycles, reassess rhythm every 2 minutes

    • Continue CPR 2-min cycles
    • Reassess rhythm after each cycle
    • Consider reversible causes
    • ETCO2 <10 mmHg after 20 min may indicate poor prognosis
    • Consult team for duration of resuscitation
  11. Path rejoins step 04Shared downstream outcome
  12. 11Action

    Asystole/PEA Management

    Non-shockable rhythm: Focus on CPR and epinephrine

    • Continue high-quality CPR
    • Epinephrine: 0.01 mg/kg IV/IO (max 1 mg) ASAP
    • Repeat epinephrine every 3-5 minutes
    • Identify and treat reversible causes (H's and T's)
  13. 12Warning

    Treat Reversible Causes (H's and T's)

    Search for and treat underlying causes

    • Hypovolemia - fluid bolus 20 mL/kg
    • Hypoxia - ensure adequate ventilation/oxygenation
    • Hydrogen ion (acidosis)
    • Hypo/Hyperkalemia - check glucose
    • Hypothermia
    • Tension pneumothorax - needle decompression
    • Tamponade (cardiac) - pericardiocentesis
    • Toxins - consider specific antidotes
    • Thrombosis (coronary/pulmonary)
  14. Path rejoins step 08Shared downstream outcome

Guideline Source

2025 AHA/AAP Guidelines for CPR and ECC - Pediatric Advanced Life Support

Clinical Safety Information

Clinical Decision Support — Not a Substitute for Clinical Judgment

Individual patient factors may require deviation from these recommendations.

Known Limitations

  • Does not address neonatal resuscitation (use NRP)
  • Assumes standard hospital resources available
  • Weight-based dosing requires accurate weight estimation
  • Does not cover post-arrest care in detail

Contraindicated Populations

neonates_under_28_days

Applicable Regions

USInternational

US: Follows AHA 2025 PALS guidelines

International: Aligned with ILCOR 2025 recommendations

Version 1Next review: 2030-01-01

Frequently Asked Questions

What is the Pediatric Cardiac Arrest (PALS 2025)?

The Pediatric Cardiac Arrest (PALS 2025) is a emergency clinical algorithm for Pediatrics. It provides a structured decision tree to guide clinical decision-making, based on 2025 AHA/AAP Guidelines for CPR and ECC - Pediatric Advanced Life Support.

What guideline is the Pediatric Cardiac Arrest (PALS 2025) based on?

This algorithm is based on 2025 AHA/AAP Guidelines for CPR and ECC - Pediatric Advanced Life Support (DOI: 10.1161/CIR.0000000000001368).

What are the limitations of the Pediatric Cardiac Arrest (PALS 2025)?

Known limitations include: Does not address neonatal resuscitation (use NRP); Assumes standard hospital resources available; Weight-based dosing requires accurate weight estimation; Does not cover post-arrest care in detail. Individual patient factors may require deviation from these recommendations.

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