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Cerebellar (Posterior Fossa) Haemorrhage - Surgical Decision (AHA/ASA 2022)

Cerebellar (Posterior Fossa) Haemorrhage - Surgical Decision (AHA/ASA 2022): Spontaneous cerebellar haemorrhage on CT (adult) → Check first: brainstem b...

Pathway Overview

13 steps

Algorithm Steps

13 total

  1. 01Start

    Spontaneous cerebellar haemorrhage on CT (adult)

    Non-traumatic intracerebral haemorrhage (ICH) in the cerebellum. Call neurosurgery early.

  2. 02Warning

    Check first: brainstem bleed, vascular cause, trauma, child

    These patients need a different plan. Deteriorating patient: do not delay surgery for vascular imaging; add CTA to the planning CT only if it causes no delay.

    • Primary brainstem (pontine) haemorrhage: surgery steps below do not apply; get neurosurgery and ICU advice
    • Age <45 y, or 45-70 y with no hypertension: CTA (± venography) to exclude AVM, aneurysm or venous thrombosis
    • Trauma or child: use a head injury or paediatric pathway
  3. 03Action

    Assess now: airway, GCS, pupils, brainstem signs, CT findings

    Protect the airway if GCS falls or airway reflexes are lost. Check GCS, pupils, cranial nerve signs and breathing pattern for deterioration or brainstem compression.

    • CT: haematoma volume (ABC/2), IVH, fourth ventricle, basal cisterns, hydrocephalus
    • FBC, INR, aPTT; anticoagulant or antiplatelet use and time of last dose
    • Admit to a neuro ICU; no neurosurgery on site: transfer to a neurosurgical centre
    • Give full active care unless the patient documented treatment limits before the ICH
  4. 04Action

    Mild to moderate ICH: if SBP 150-220 mmHg, lower SBP to 140 mmHg

    SBP >220 mmHg, large ICH or surgery needed: lower with caution and set the SBP target with neurosurgery. Otherwise start within 2 h of onset, reach target within 1 h and titrate smoothly.

    • Keep SBP 130-150 mmHg
    • Do not lower SBP below 130 mmHg (potentially harmful)
    • Avoid peaks, large swings and a fall in SBP of more than 70 mmHg
    • IV agent per local protocol (e.g. labetalol, clevidipine). No labetalol in asthma, bradycardia or AV block
  5. 05Action

    On an anticoagulant: stop it and reverse now, before surgery

    Give reversal as soon as ICH is diagnosed. Do not wait for the INR if a recent dose is likely. Warfarin: aim INR <1.3 as soon as possible; recheck INR after PCC.

    • Warfarin (adult): vitamin K 5-10 mg IV plus 4F-PCC (Beriplex) 50 IU/kg IV, max 5000 IU; lower PCC dose if INR 1.5-1.9. Only Prothrombinex-VF stocked: follow local protocol
    • Dabigatran (adult): idarucizumab 5 g IV (2 x 2.5 g)
    • Apixaban, rivaroxaban or edoxaban: 4F-PCC. Dose: see local haematology protocol (andexanet alfa is not TGA-registered)
    • Heparin or LMWH (enoxaparin): protamine; LMWH is only partly reversed. Dose: see product information
  6. 06Action

    On an antiplatelet: no platelet transfusion unless emergency surgery

    Platelet transfusion for antiplatelet-related ICH without surgery is potentially harmful.

    • Aspirin and emergency neurosurgery: platelet transfusion may be considered
    • Ticagrelor is not reversed by platelet transfusion
    • Desmopressin: benefit uncertain
    • Any ICH: tranexamic acid and factor VIIa are not established; do not give routinely
  7. 07Decision

    Deterioration, brainstem compression, obstructive hydrocephalus or ICH ≥15 mL?

    Any one of these is an indication for immediate surgery. Estimate haematoma volume by ABC/2.

  8. If Yes
    1. 08Warning

      Surgery indicated: immediate haematoma evacuation, with or without EVD

      Surgical removal reduces mortality compared with medical care alone (AHA 2022 COR 1). Functional benefit is not proven.

      • Do not use EVD alone for obstructive hydrocephalus: may be harmful (worse if basal cisterns compressed) and may not relieve brainstem compression or ischaemia
      • Primary brainstem haemorrhage: this step does not apply
      • Reverse anticoagulation before surgery (see above)
    2. 09Action

      Surgery indicated: suboccipital craniectomy and haematoma evacuation

      Neurosurgeon chooses the approach. No trial compares techniques.

      • Suboccipital decompression plus evacuation: trend to better outcome than evacuation alone (one retrospective study)
      • Hydrocephalus: place EVD together with evacuation
      • Endoscopic or stereotactic evacuation: evidence limited
    3. 10Action

      After surgery: neuro-ICU care

      Continue BP target and correction of coagulation.

      • Frequent neuro checks; CT at once if deterioration
      • Intermittent pneumatic compression from the day of diagnosis
      • Low-dose heparin or LMWH: timing with neurosurgery (may start 24-48 h after ICH onset if stable)
    4. 11Outcome

      Outcome after surgery

      Surgery improves survival. Benefit for functional outcome is not proven.

    If No
    1. 12Action

      No surgical indication now: medical care with close monitoring

      For cerebellar ICH <15 mL with no deterioration, no brainstem compression and no hydrocephalus.

      • Neuro ICU; frequent neuro checks
      • CT at once if GCS falls or new brainstem signs
      • Surgery at once if deterioration, brainstem compression or hydrocephalus develops
      • Intermittent pneumatic compression from the day of diagnosis. Low-dose heparin or LMWH may start 24-48 h after onset if the haematoma is stable on CT
    2. 13Outcome

      Outcome with medical care

      Keep monitoring. Operate if the patient deteriorates.

Guideline Source

AHA/ASA 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage

Clinical Safety Information

Clinical Decision Support — Not a Substitute for Clinical Judgment

Individual patient factors may require deviation from these recommendations.

Known Limitations

  • Adults with spontaneous cerebellar ICH only; not for primary brainstem haemorrhage, trauma or children
  • No randomised trials: surgery reduces mortality in observational data, but functional benefit is not proven
  • Timing of surgery and choice of surgical technique are not established
  • Reversal doses are for adults; follow local haematology protocol for DOAC reversal

Contraindicated Populations

ChildrenPrimary brainstem haemorrhageTraumatic posterior fossa haematoma

Applicable Regions

USEUAUGlobal

AU: Andexanet alfa and nicardipine are not on the ARTG. 4F-PCC (Beriplex) is registered; where only Prothrombinex-VF (3F-PCC) is stocked, follow local protocol.

EU: ESO-EANS 2025 ICH guideline: suggests surgical evacuation of cerebellar haematoma >15 mL to improve survival (weak recommendation, very low certainty).

US: AHA/ASA 2022: immediate surgical evacuation, with or without EVD, for cerebellar ICH with deterioration, brainstem compression, obstructive hydrocephalus or volume ≥15 mL (COR 1, LOE B-NR).

Version 2Next review: 2027-09-30

Frequently Asked Questions

What is the Cerebellar (Posterior Fossa) Haemorrhage - Surgical Decision (AHA/ASA 2022)?

The Cerebellar (Posterior Fossa) Haemorrhage - Surgical Decision (AHA/ASA 2022) is a emergency clinical algorithm for Neurosurgery. It provides a structured decision tree to guide clinical decision-making, based on AHA/ASA 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage.

What guideline is the Cerebellar (Posterior Fossa) Haemorrhage - Surgical Decision (AHA/ASA 2022) based on?

This algorithm is based on AHA/ASA 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage (DOI: 10.1161/STR.0000000000000407).

What are the limitations of the Cerebellar (Posterior Fossa) Haemorrhage - Surgical Decision (AHA/ASA 2022)?

Known limitations include: Adults with spontaneous cerebellar ICH only; not for primary brainstem haemorrhage, trauma or children; No randomised trials: surgery reduces mortality in observational data, but functional benefit is not proven; Timing of surgery and choice of surgical technique are not established; Reversal doses are for adults; follow local haematology protocol for DOAC reversal. Individual patient factors may require deviation from these recommendations.

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