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Colorectal SurgeryDiagnostic

Colorectal Cancer Staging Workup (NCCN 2024)

Colorectal Cancer Staging Workup (NCCN 2024): Colorectal Cancer Diagnosed → Baseline Workup → Staging Imaging → Clinical Stage → Localized Disease.

Pathway Overview

9 steps

Algorithm Steps

9 total

  1. 01Start

    Colorectal Cancer Diagnosed

    Biopsy-proven adenocarcinoma

  2. 02Action

    Baseline Workup

    CBC, CMP, CEA, LFTs

    • Complete colonoscopy if not done
    • Pathology review: differentiation, LVI
  3. 03Action

    Staging Imaging

    CT chest/abdomen/pelvis with IV contrast

    • Rectal: MRI pelvis for T/N staging
    • Liver MRI if indeterminate lesions
  4. 04Decision

    Clinical Stage

    • Stage I-III (localized)
    • Stage IV (metastatic)
  5. 05Action

    Localized Disease

    Proceed to surgical planning

  6. 06End

    Surgical Resection

    Oncological resection with adequate margins

  7. 07Action

    Metastatic Disease

    MDT discussion required

  8. 08End

    Multidisciplinary Review

    Chemo, targeted therapy, resectable mets?

  9. 09Action

    Molecular Testing

    MSI/MMR, RAS/BRAF, HER2 (if applicable)

Guideline Source

NCCN Clinical Practice Guidelines in Oncology: Colon/Rectal Cancer

Clinical Safety Information

Clinical Decision Support — Not a Substitute for Clinical Judgment

Individual patient factors may require deviation from these recommendations.

Known Limitations

  • Staging may change after surgical resection
  • PET-CT utility depends on clinical scenario
  • MSI/MMR testing increasingly important

Applicable Regions

USAUUKEU

AU: Cancer Council Australia guidelines

UK: NICE colorectal cancer guidelines

US: NCCN guidelines standard

Version 1Next review: 2028-01-01

Frequently Asked Questions

What is the Colorectal Cancer Staging Workup (NCCN 2024)?

The Colorectal Cancer Staging Workup (NCCN 2024) is a diagnostic clinical algorithm for Colorectal Surgery. It provides a structured decision tree to guide clinical decision-making, based on NCCN Clinical Practice Guidelines in Oncology: Colon/Rectal Cancer.

What guideline is the Colorectal Cancer Staging Workup (NCCN 2024) based on?

This algorithm is based on NCCN Clinical Practice Guidelines in Oncology: Colon/Rectal Cancer (DOI: 10.6004/jnccn.2024.0001).

What are the limitations of the Colorectal Cancer Staging Workup (NCCN 2024)?

Known limitations include: Staging may change after surgical resection; PET-CT utility depends on clinical scenario; MSI/MMR testing increasingly important. Individual patient factors may require deviation from these recommendations.

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